Metronidazole (Flagyl) Toxicity in Dogs

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Metronidazole (Flagyl) is a commonly used and very effective antibiotic. It is most frequently used to treat gastrointestinal parasites, primarily Giardia. It has also been used to treat severe infections, usually in combination with other antibiotics. Unfortunately, as with all drugs, toxicity and adverse effects can occur. However, toxicity from metronidazole is uncommon and is generally associated with prolonged use (many weeks) or high doses of the drug. Animals with underlying liver disease are more prone to metronidazole toxicity. Toxic levels of metronidazole affect the brain and equilibrium.What to Watch For
Not eating
Vomiting
Staggering or difficulty walking
Involuntary and constant eye movements (nystagmus)
Lethargy
SeizuresDiagnosisThe diagnosis of metronidazole toxicity is based on physical exam findings as well as a history of recent drughttp://www.petplace.com/dogs/metronidazole-flagyl-toxicity-in-dogs/page1.aspx