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Wednesday, January 28, 2009

Zithromax (azithromycin)

How does it work?Zithromax capsules and suspension contain the active ingredient azithromycin, which is a type of medicine called a macrolide antibiotic. (NB. Azithromycin is also available without a brand name, ie as the generic medicine.) Azithromycin is used to treat infections caused by bacteria. Azithromycin works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. Azithromycin therefore stops the spread of infection and remaining bacteria are killed by the body's immune system or eventually die. Azithromycin is a broad-spectrum antibiotic that is active against a wide variety of bacteria that cause a wide variety of infections. Azithromycin may be used to treat infections of the upper or lower airways, skin or soft tissue, or ears. It is also used to treat the sexually-transmitted infection chlamydia. To make sure the bacteria causing an infection are susceptible to azithromycin your doctor may take a tissue sample, for example a swab from the throat or skin.What is it used for?
Bacterial infection of the lungs and airways (chest or lower respiratory tract infection, eg pneumonia, bronchitis).
Bacterial infections of the nasal passages, sinuses or throat (upper respiratory tract infection, eg sinusitis, tonsillitis, pharyngitis).
Bacterial infections of the middle ear (otitis media).
Bacterial infections of the skin or soft tissue.
Chlamydia.Warning!
Zithromax capsules should be taken at least one hour before or two hours after food. Zithromax suspension can be taken with food.
Unless your doctor tells you otherwise, it is important that you finish the prescribed course of this antibiotic medicine, even if you feel better or it seems the infection has cleared up. Stopping the course early increases the chance that the infection will come back and that the bacteria will grow resistant to the antibiotic.
Broad-spectrum antibiotics can sometimes cause inflammation of the bowel (colitis). For this reason, if you get diarrhoea that becomes severe or persistent or contains blood or mucus, either during or after taking this medicine, you should consult your doctor immediately.
All antibiotics can sometimes result in overgrowth of organisms that are not susceptible to the antibiotic, in particular fungi. You should let your doctor know if you think you have developed any other infections while you are taking this medicine, so that they can be treated appropriately.Use with caution in
Severely decreased kidney function.
Abnormal heart rhythm seen on a heart monitoring trace (ECG) as a 'prolonged QT interval', or people at risk of this (your doctor will know).Not to be used in
Allergy to macrolide or ketolide type antibiotics, eg erythromycin.
Severe liver disease.
Zithromax capsules are not suitable for children weighing under 45kg. The suspension should be used for children who weigh under 45kg.
This medicine is not recommended for children under six months of age.This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.Pregnancy and breastfeedingCertain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
The safety of this medicine for use during pregnancy has not been established. It is not recommended for use in pregnancy unless considered essential by your doctor. Seek medical advice from your doctor.
This medicine passes into breast milk. It is not recommended for use during breastfeeding unless considered essential by your doctor. Seek medical advice from your doctor.

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